Comparing combination of two drugs namely 0.25 percent Ropivacaine and Dexmedetomidine when used with Clonidine in nerve blocks to compare pain relief in patients aged 18 to 64 yrs who are posted for shoulder arthroscopic surgeries

Comparison of 0.25 percent Ropivacaine with Dexmedetomidine vs Clonidine as an adjuvant in Interscalene Brachial plexus block for post operative analgesia in shoulder arthroscopy. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/095269

Enrollment

Registered

2025-09-22

Start date

Unknown

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group 1 - Inj 0.25 % Ropivacaine + Clonidine: Patients randomised into group 1 will receive an interscalene brachial plexus block with 0.25 percent Ropivacaine plus Clonidine. Control I

Eligibility

Inclusion criteria

Inclusion criteria: 1) Age group- 18 - 59years, 2) Scheduled for elective shoulder arthroscopic surgeries under GA 3) ASA Grade I and II patients

Exclusion criteria

Exclusion criteria: 1) Patient refusal 2) Bleeding disorders 3) Patients with known local anesthetic sensitivity 4) morbidly obese patients 5) Previous h/o upper limb nerve damage 6) Respiratory insufficiency 7) Infection at the block location.

Design outcomes

Primary

Measure	Time frame
To compare the effect of 12 ml of 0.25% Ropivacaine + Dexmedetomidine vs 12 ml of 0.25% Ropivacaine + Clonidine on duration of analgesia when used in Interscalene Brachial Plexus block for shoulder arthroscopy.Timepoint: Postoperatively VAS scores of patients will be assessed for 2,4,6,8,10,12,24 hrs	—

Secondary

Measure	Time frame
1)VAS Score over 24 hours 2)Time to first request of post operative analgesia 3)Total IV PCA Fentanyl consumption over 24 hrs Timepoint: Vas score will be assessed at 2,4,6,8,10,12,24 hrs post block	—

Countries

India

Contacts

Public ContactDr Sandra Monis

St. Johns Medical College and Hospital, Bangalore

drnischala01@gmail.com9535148078

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026