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A study to compare the efficacy of 0.5% bupivacaine with 30 micrograms buprenorphine and 0.5% bupivacaine with 60 micrograms buprenorphine for epidural Anaesthesia in lower limb orthopaedic surgeries on two group of participants that are exposed with this drugs .

A Comparative Study of Epidural 0.5 percent Bupivacaine With 30 micrograms [mcg]Buprenorphine Versus Epidural 0.5 percent Bupivacaine With 60 micrograms [mcg]Buprenorphine For Lower Limb Orthopaedic Surgeries-Randomised Control Study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/095249
Enrollment
80
Registered
2025-09-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Drug: 15 ml of 0.5% bupivacaine with 30 mcg of buprenorphine for epidural anaesthesia in lower limb orthopaedic surgery patients for a duration of 1 year . Control Intervention1: Drug:

Sponsors

Government medical college,Ananthapuramu
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted for elective lower limb orthopaedic surgeries. Patients in ASA grade 1,2,3 .

Exclusion criteria

Exclusion criteria: Patients with contraindications for epidural anaesthesia. Uncooperative patients /patient refusal. Pregnant Patients with Spinal deformities Patients with hypersensitivity to the study drug. Coagulation defect /Anticoagulant therapy Sepsis

Design outcomes

Primary

MeasureTime frame
Outcomes were assessed and compared in terms of time taken for the onset of sensory blockade ,motor blockade,duration of motor blockade , duration of sensory analgesia and hemodynamic changes. Timepoint: 2 weeks, 4 weeks and 8 weeks—

Secondary

MeasureTime frame
Side effects recorded and comparedTimepoint: 2 weeks,4 weeks & 8 weeks—

Countries

India

Contacts

Public ContactYuvakeerthana R

Government medical college,Ananthapuramu

sreeharimbbs@gmail.com9492495772

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026