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Comparison between neostigmine and Sugammadex in terms of efficacy and safety as reversal agent in major surgeries under general anaesthesia

comparison of neuromuscular recovery profile using neostigmine and sugammadex as reversal agents in major surgeries under general anaesthesia - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/095245
Enrollment
150
Registered
2025-09-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K911- Postgastric surgery syndromes

Interventions

Intervention1: Giving Neostigmine and sugammadex: To determine the efficacy and safety of Sugammadex over Neostigmine as reversal agents in major surgeries Control Intervention1: neostigmine and sugam

Sponsors

Department of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients undergoing major surgeries with ASA PS I,II,BMI Below 30kg/m2, who gave informed consent.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
comparison of time between administration of reversal agent to safe tracheal extubationTimepoint: Time point between giving reversal agent to tracheal extubation—

Secondary

MeasureTime frame
compare quality of neuromuscular recovery, hemodynamic variables, adverse effectsTimepoint: immediate post operative period—

Countries

India

Contacts

Public ContactDr TAPAS GHOSE

I.P.G.M.E. and R. and SSKM Hospital

g.tapas@gmail.com9903745071

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026