Health Condition 1: O746- Other complications of spinal andepidural anesthesia during labor and delivery
Conditions
Interventions
Intervention1: Intravenous dexamethasone: Patients will receive intravenous dexamethasone 8mg in 10ml saline over 1 minute in preoperative area 15 minutes prior to subarachnoid block
Control Intervent
Sponsors
Dr Nisha Sangwan
Eligibility
Inclusion criteria
Inclusion criteria: Pregnant women ASA PS 2, singleton pregnancy with gestational age more than 37 weeks scheduled for elective cesarean delivery under spinal anaesthesia
Exclusion criteria
Exclusion criteria: Patients with history suggestive of gestational or chronic diabetes and hypertensive disorders of pregnancy Recent intake of steroids BMI of more than 35 kg/m 2 Previous 2 caesarean section History of allergy to the study drugs Any contraindication to regional anaesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate and compare the incidence of spinal anaesthesia mediated hypotension in parturients receiving prophylactic intravenous dexamethasone and mephentermine versus mephentermine aloneTimepoint: Till 20 minutes after spinal anaesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| Haemodynamic parameters like heart rate and systolic blood pressureTimepoint: At baseline, every 2 minutes and 20 minutes after spinal anaesthesia and then at every 5 minute;Time to achieve T6 level of blockTimepoint: ;Total dose of mephentermine(mg) administeredTimepoint: ;Time to first rescue mephentermine bolusTimepoint: ;Neonatal Apgar scoreTimepoint: At 1 minute and 5 minutes | — |
Countries
India
Contacts
Public ContactDr Rashmi Virmani
Esic medical college and hospital
Outcome results
None listed