FindTrial
Sign In

Outcomes of a Single-Session Internal Radiation Approach for Cervical Cancer After External Radiation

Clinical outcomes of cervical cancer with single application in situ HDR brachytherapy involving 8Gy x 3 fractions following a course of pelvic EBRT - a prospective clinical study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/095184
Enrollment
48
Registered
2025-09-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecified

Interventions

Intervention1: Brachytherapy: in situ HDR brachytherapy 8Gy x 3 fractions Control Intervention1: NOT APPLICABLE: NOT APPLICABLE

Sponsors

Intramural Research Fund Jawaharlal Institute of Postgraduate Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Biopsy-proven newly diagnosed carcinoma cervix Stage IB, IIA, IIB, IIIB; without lower one third of vagina involvement. ECOG 0-2 Age less than 70 years No major life threatening complications Willingness to comply with study procedures and provide informed consent

Exclusion criteria

Exclusion criteria: ECOG 3 or more Prior pelvic radiotherapy Uncontrolled diabetes and hypertension Prior history of DVT/ Pulmonary embolism Pregnancy or lactating women Lower one-third involvement of vagina in any stage

Design outcomes

Primary

MeasureTime frame
To assess the locoregional control up to 6 months post radiotherapy in patients with cervical cancer.Timepoint: 6 months after treatment completion—

Secondary

MeasureTime frame
To evaluate early acute and acute toxicities (less than 3months, and less than 6months respectively) associated using CTCAE Version 5.0 toxicity criteriaTimepoint: 3 months, 6 months;To evaluate late toxicities (more than 6months) associated with the therapeutic pelvic irradiationTimepoint: 1 year—

Countries

India

Contacts

Public ContactDr Parthasarathy Vedasoundaram

Jawaharlal Institute of Postgraduate Medical Education and Research

dr_patchu2003@yahoo.co.in9443601748

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026