Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Tranexamic Acid: 500mg(5 ml) of tranexamic acid instilled endobronchial as the lesion is visible
Control Intervention1: Placebo: Normal Saline 5 ml endobronchial as soon as the lesion i
Sponsors
All India Institute of Medical Sciences New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Patients with endobronchial lesion in form of growth, infiltration, nodularity as seen during bronchoscopy
Exclusion criteria
Exclusion criteria: Any contraindication for biopsy that is coagulopathy or hemodynamically unstable condition for bronchoscopy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determine the difference in the proportion of patients with moderate to severe between the intervention and the control arm Timepoint: During procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety End Points: The incidence of thromboembolic events, including myocardial infarction, stroke, deep vein thrombosis or pulmonary embolism.Timepoint: 1 month;Difference in the proportion of patients with each grade of bleeding (1 to 4) as assessed by the bronchoscopist performing the procedure. Timepoint: During procedure;The difference in the duration of the procedure Timepoint: During procedure;Premature interruption of procedureTimepoint: During procedure;Bronchoscopist graded patient s tolerance of the procedure using the VAS scale Timepoint: During procedure | — |
Countries
India
Contacts
Public ContactPratyakcha Rai
AIIMS, Delhi
Outcome results
None listed