Health Condition 1: J00-J99- Diseases of the respiratory system
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children aged 5 to 18 years diagnosed with asthma based on GINA (Global Initiative for Asthma) guidelines. 2. Children who are able to perform impulse oscillometry (IOS) measurements reliably.
Exclusion criteria
Exclusion criteria: 1. Children with acute asthma exacerbation at the time of testing. 2. Presence of other chronic respiratory diseases (e.g., cystic fibrosis, bronchopulmonary dysplasia, congenital lung malformations). 3. History of chronic lung infections (e.g., tuberculosis, recurrent pneumonia). 4. Children with neuromuscular disorders or developmental delays or craniofacial abnormalities that may interfere with proper IOS testing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of IOS parameters (R5, R20, R5 R20, X5, AX, and Fres) across clinically classified asthma severity groups.Timepoint: Single time point assessment | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of the sensitivity & diagnostic accuracy of IOS & PEFR in reflecting asthma severity, assessing bronchodilator reversibility by measuring changes in IOS & PEFR before & after nebulised salbutamol, & evaluation of the association between total serum IgE levels & IOS parameters.Timepoint: Single time point assessment | — |
Countries
India
Contacts
Department of Paediatrics, Kasturba Medical College, Manipal