Study to see the effect of Gandharyadi Ghrita in the Management of Ardhavabhedaka (Migraine)

A Randomized Clinical study of Nasya with Gandharyadi Ghrita in the Management of Ardhavabhedaka wsrt Migraine - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/095169

Enrollment

100

Registered

2025-09-22

Start date

Unknown

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G430- Migraine without aura

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients with a history of at least five migraine episodes, but not currently experiencing an active episode, were enrolled in this clinical trial. 2) Moderate to Severe Migraine Patients. 3) Age Group: 25 Yrs. To 50 Yrs. 4) Sex : Male And Female Both 5) The Volunteers Who Duly Signed the Concern Form Will Be Considered. 6) Yogya for Nasya Karma.(as per classical indications). 7) Ability to follow the treatment schedule and attend follow-up visits.

Exclusion criteria

Exclusion criteria: 1)Structural brain pathology,incranial lesion or history of head trauma. 2)Action episode of Migraine. 3)Non vascular and psychiatric disorder. 4)severe systemic illness like uncontrolled diabetes, hypertension, epilepsy. 5)H/O or K/C/O bleeding disorder. 6) known allergy to ingredients of Gandharvyadi ghrit or shadbindu taila

Design outcomes

Primary

Measure	Time frame
1.Reduction in frequency of migraine (Ardhavabhedak) attacks: Measured as the number of episodes per month before and after intervention. 2.Reduction in intensity of headache: Assessed using the MIDAS Scale. Timepoint: Sustainability of nasya karma will be taken by using Midas scale interval of 1st 15th 30th 60th 90th 120th day	—

Secondary

Measure	Time frame
1. Reduction in duration of migraine episodes: Measured in hours per episode before and after treatment. 2. Improvement in associated symptoms: Such as nausea, vomiting, photophobia, phonophobia is using a symptom severity grading scale or patient diary. 3. Quality of life improvement: Assessed using a validated tool like MIDAS Scale. 4. Adverse events related to Nasya therapy: Monitoring for any side effects or discomfort caused by the intervention. 5. Nasya Karma offers cost-effective and sustained relief in Ardhavabhedaka by reducing symptoms, improving sleep, and enhancing mental clarity, with added social and economic benefits like fewer sessions, minimal resource use, and reduced long- term medication needs. Timepoint: sustainability of Nasya Karma will be taken by using MIDAS scale on interval of 1st 15th 30th 60th 90th 120th day	—

Measure

Time frame

1. Reduction in duration of migraine episodes: Measured in hours per episode before and after treatment. 2. Improvement in associated symptoms: Such as nausea, vomiting, photophobia, phonophobia is using a symptom severity grading scale or patient diary. 3. Quality of life improvement: Assessed using a validated tool like MIDAS Scale. 4. Adverse events related to Nasya therapy: Monitoring for any side effects or discomfort caused by the intervention. 5. Nasya Karma offers cost-effective and sustained relief in Ardhavabhedaka by reducing symptoms, improving sleep, and enhancing mental clarity, with added social and economic benefits like fewer sessions, minimal resource use, and reduced long- term medication needs. Timepoint: sustainability of Nasya Karma will be taken by using MIDAS scale on interval of 1st 15th 30th 60th 90th 120th day

—

Countries

India

Contacts

Public ContactDr Prajakta korde

Bharati Vidyapeeth (Deemed to be University) College and Hospital of Ayurveda Pune 43

drsantoshchavan5@gmail.com9822249807

Outcome results