Health Condition 1: O- Medical and Surgical Health Condition 2: H679- Otitis media in diseases classified elsewhere, unspecified ear
Conditions
Interventions
Intervention1: preemptive analgesia Group B: local infiltration nerve block of injection Bupivacaine 0.5% in dose of 3mg/kg upto 15 ml volume of drug at surgical inscion site in patients undergoing ty
Sponsors
VCSG Govt Institute of Medical Sciences and Research
Eligibility
Inclusion criteria
Inclusion criteria: ASA GRADE1 patients with Chronic otitis media undergoing TYMPANOPLASTY under GENERAL ANAESTHESIA. Weight above 40kg
Exclusion criteria
Exclusion criteria: ASA 2, 3,4, Weight below 40kgs patients allergic to bupivacaine. patients on Beta blockers or other antihypertensive drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study effect of pre-emptive analgesia on hypothalamic pituitary adrenal neuroendocrinal stress response axis during perioperative period by measuring levels of blood adrenaline , cortisol and glucose in patient undergoing surgery in general anaesthesiaTimepoint: Stress response evaluated measuring Serum Adrenaline, Cortisol and Blood Glucose level at Basal Level, 10 mins post intubation, 3 mins post incision , 63 mins post incision, 123 mins post incision and 1hr after extubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| To corelate perioperatiove stress response with haemodynamic clinical parameters of Blood pressure , Mean arterial pressure heart rate Visual analogue score at end of surgery after extubation.Timepoint: Heart Rate Blood Pressure Mean arterial pressure Temperature monitoring will be done at Basal level, followed by every 2 mins after endotracheal intubation during perioperative period till the end of surgery. Analyse Visual Analogue Scale at end of surgery every 10 minutes after Extubation upto 1hr. | — |
Countries
India
Contacts
Public ContactDr Satyendra Yadav
VCSGGIMS and RESEARCH associated HNB BASE TEACHING HOSPITAL
Outcome results
None listed