Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Fentanyl: Given at induction 2 mcg per kilo followed by 1 mcg per kilo every hour till end of procedure
Control Intervention1: Dexmedetomine 100 mcg and ketamine 50 mg diluted with 48 m
Sponsors
SIMS Hospitals
Eligibility
Inclusion criteria
Inclusion criteria: Patients of American society of anaesthesiology grade 1 and 2 Patients weighing between 40 and 80 kilos All genders Patients admitted for minimally invasive abdominal and pelvic surgeries Patients willing to participate in the study
Exclusion criteria
Exclusion criteria: Patients of American society of anaesthesiology grades 3 and above Pregnant and lactating women Patients with allergies to any of the drugs- general and local anaesthetic agents being used Patients with h/o neuromuscular disorders, malignant hyperthermia or susceptible individuals Patients with any degree of heart block or with pacemaker Minimally invasive surgeries getting converted to open surgeries Patients with anticipated possible difficult airway Patients participating in any other clinical study Patients not willing to participate in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare intraoperative combination of dexmedetomidine and ketamine (ketodex) with that of intraoperative fentanyl in terms of post operative analgesia by means of Visual Analogue Scale (VAS)Timepoint: Immediate post op, every hour till 6 hours postoperative | — |
Secondary
| Measure | Time frame |
|---|---|
| To monitor & quantify adverse effects of ketodex in terms of sedation, bradycardia, hypotension & emergence delirium To quantify efficacy of analgesia of ketodex in terms of requirement of postoperative rescue analgesiaTimepoint: postoperative period immediately & every hour till 6 hours post operative | — |
Countries
India
Contacts
Public ContactDr Balachandran
SIMS Hospitals
Outcome results
None listed