Health Condition 1: L700- Acne vulgaris
Conditions
Interventions
Intervention1: randomized control trial: 2 arm study on oral isotretinoin therapy . Group A : pulse therapy for 12 weeks and Group B : conventional therapy for 12 weeks
Control Intervention1: oral is
Sponsors
Karpaga Vinayaga Institute Of Medical Sciences And Research Center
Eligibility
Inclusion criteria
Inclusion criteria: Patients with acne vulgaris on face more than equal to 18 yrs with moderate grade, who understands the protocol and willing to give informed consent
Exclusion criteria
Exclusion criteria: patient who are tring to conceive , pregnant , breast feeding , with deranged liver function test and renal function test ,allergic to isotretinoin ,dyslipidemia .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| percentage improvement , patient satisfaction.Timepoint: percentage of improvement assessed at 2,4,8,12 ,16and 20 weeks . patient satisfaction assessed at 20 week. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Liver function test , 2. Lipid function test , 3.Patient satisfaction , 4.Clinical photographs at before & after treatment .Timepoint: 1.changes in AST & ALT measuring at 6, 12, 20 week. 2.changes in cholesterol, triglycerides, LDL, HDL measured at 6, 12 ,20 weeks 3.measured at 20 week using likert scale, 4.Clinical photographs at base line & at 20 week treatment . | — |
Countries
India
Contacts
Public ContactDr Bhagya M Baiju
Karpaga Vinayaga Institute Of Medical Sciences And Research Center
Outcome results
None listed