Skip to content

Comparison of 2 drugs ( Ropivacaine and Bupivacaine) in spinal anaesthesia to evaluate effect on post operative urine retention in patients undergoing after surgery for Varicose veins

Comparison of Equipotent Doses of Hyperbaric Ropivacaine and Bupivacaine in Spinal Anaesthesia to Evaluate Effect on Postoperative Urinary Retention in Patients Undergoing Endovenous Laser Ablation for Varicose Veins: A Randomised Double Blind study - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/095111
Enrollment
66
Registered
2025-09-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I832- Varicose veins of lower extremities with both ulcer and inflammation

Interventions

Intervention1: Ropivacaine vs Bupivacaine: Comparison of Equipotent doses of hyperbaric inj. Ropivacaine 0.75 percent 2.5 ml and inj. Bupivacaine 0.5 percent 2.5 ml in spinal anaesthesia to evaluat

Sponsors

Rabindranath Tagore Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 18-60 years of both sex American society of Anesthesiologists physical status I-II Height 150-175 centimetres Weight 40-90 kilograms

Exclusion criteria

Exclusion criteria: Patient refusal Patient with any contraindication to subarachnoid block like coagulopathies or anticoagulant medication, raised intracranial pressure, local injection site infection, severe stenotic valvular heart disease. Patients having Pregnancy, neurological, psychiatric, renal calculus, prostatic disease, diabetes with autonomic neuropathy, urinary tract disease Patients on beta blockers, alpha 2 agonists and diuretics therapy that may interfere with micturition Any patients with hypertension, cardiac, renal, liver, endocrine, haematological or any coexisting systemic medical comorbidity Obesity (body mass index more than 30kg per meter square ), opioid drug addiction Patients who need to be catheterized preoperatively on table by surgeon in view of any coexisting illness, or risk of postoperative urinary retention History of allergy to study drugs.

Design outcomes

Primary

MeasureTime frame
Time to void urine post spinal block measured in minutesTimepoint: Time to void urine post spinal block measured in minutes

Secondary

MeasureTime frame
Need for urinary catheterisation due to inability to void urine 8 hours after the surgery despite having distended bladder or earlier if patient being uncomfortable due to POUR ( Complications due to POUR postoperatively such as abdominal pain, nausea. vomiting, hypotension /hypertension, bradycardia /tachycardia, arrhythmia and their treatment Sensory and motor onset Maximal level of sensory and motor block Intraoperative haemodynamic profile Intraoperative complications such as hypotension, bradycardia, nausea, vomiting, pruritus, shivering Quality of anaesthesia by four grade scale regarding need of supplementation Intraoperative and postoperative fluids givenTimepoint: Upto 24 hours postoperatively

Countries

India

Contacts

Public ContactDr Mrinalini Yadav

Rabindranath Tagore Medical College

uditanaithani@gmail.com9829414752

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026