Comparison of pain relief during labour using Ropivacaine alone or with fentanyl through epidural injection

A Comparative study of 0 point 1 percent Ropivacaine with or without Fentanyl for Epidural Labour analgesia A Randomized Controlled study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/095099

Enrollment

Registered

2025-09-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80-O82- Encounter for delivery

Interventions

Intervention1: Ropivacaine Vs Ropivacaine with Fentanyl: 0.1% Ropivacaine with or without Fentanyl for epidural labour analgesia for 1 year Control Intervention1: Ropivacaine: 0.1% Ropivacaine for epi

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 35 years 2. ASA grade I and II in active stage of labour (greater than or equal to 3 cm dilatation) 3. Primigravida 4. Singleton pregnancy 5. Vertex presentation 6. Uncomplicated pregnancy 7. Parturients requesting labour analgesia

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. ASA grade III and IV 3. Age greater than 35 years and less than 18 years 4. Multipara patients(greater than 2 children) 5. Comorbid conditions like Severe cardiac disease, Severe Pregnancy induced Hypertension, Eclampsia, Severe anemia, Psycological/Neurological disease 6. Complicated preganancies like Cephalo Pelvic disproportion, Breech presentation, Cord around neck and Previous Caesarean section. 7. Local sepsis 8. Altered coagulation profile 9. Bleeding disorders, thrombocytopenia 10. Spinal deformities 11. History of allergy to study drug

Design outcomes

Primary

Measure	Time frame
To compare the VAS score in both groupsTimepoint: 0,5,15,30,45,60,90 minutes,every hourly maximum up to 8hrs	—

Secondary

Measure	Time frame
Time of onset of analgesia,Total dose of analgesia required,Total duration of labour,Neonatal outcome,Patient satisfaction scoreTimepoint: 0,5,15,30,45,60,90 min,every hourly maximum up to 8hrs, APGAR Score at 1 & 5 min.	—

Countries

India

Contacts

Public ContactDr Shivaleela Muthyala

RNT Medical College & MB Hospital,Udaipur.

devendraanaes@yahoo.in9829623028

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026