Comparison of two injectable drug combination(Dexmedetomidine-Ketamine and Magnesium sulphate-Ketamine)for passing tube (Endotracheal tube) via nose with help of video in awake patients.

Comparison of Dexmedetomidine - Ketamine and Magnesium Sulphate - Ketamine Combination as a Sedation for Awake Fibreoptic Intubation in Adult Patients Undergoing Elective Surgeries Under General Anesthesia: A Prospective Randomised Double - Blinded Study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/095090

Enrollment

Registered

2025-09-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: S320- Fracture of lumbar vertebra Health Condition 3: K806- Calculus of gallbladder and bile duct with cholecystitis Health Condition 4: G55- Nerve root and plexus compressionsin diseases classified elsewhere Health Condition 5: C509- Malignant neoplasm of breast of unspecified site Health Condition 6: S499- Unspecified injury of shoulder andupper arm Health Condition 7: K403- Unilateral inguinal hernia, with obstruction, without ga

Interventions

Intervention1: AWAKE FIBREOPTIC INTUBATION: Comparison between IV Dexmedetomidine-Ketamine and Magnesium sulphate-Ketamine on Intubating conditions during Awake Fibreoptic Intubation Control Intervent

Eligibility

Inclusion criteria

Inclusion criteria: Patients with ASA Physical Status I and II, Patients with Mallampati Class I and II

Exclusion criteria

Exclusion criteria: Patient refusal Patients with history of allergy to study drugs Pregnancy and Lactation Patienst with nasal infection, complete obstruction and any contraindication to nasal intubation Patient with history of unstable angina or myocardial infarction and complete heart block Patients with any known cardiac, respiratory, renal or hepatic disease Psychiatric or neurological disease or seizure disorder Patients with history of bleeding disorders

Design outcomes

Primary

Measure	Time frame
Cough score (severity of cough) during awake fibreoptic intubationTimepoint: During awake fibreoptic intubation(2 mins)	—

Secondary

Measure	Time frame
Intubation comfort score POst intubation behaviour score/assessment Postoperative patient satisfaction score Ramsay sedation scale score Haemodynamics Side effects, complications if anyTimepoint: Upto 6-hour post operatively	—

Countries

India

Contacts

Public ContactDrG Manisha

R.N.T Medical college

drsanchoudhary@gmail.com9462102856

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026