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Comparing Two Types of Chitosan Gels for Treating Gum Pockets and Their Impact on Saliva Enzyme Levels in Men and Women

Comparing Thermosensitive and Non-Thermosensitive Chitosan gels in treating periodontal pockets and their effect on Salivary Pyruvate kinase levels in age matched men and women: a split-mouth clinical study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/095081
Enrollment
46
Registered
2025-09-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: scaling and root planing with intra pocket local drug delivery: all patients will undergo non-surgical periodontal therapy and were divided into three groups: Group A (n=18) received C

Sponsors

Panineeya Mahavidyalaya Institute of Dental Sciences and Research centrer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy. Patients who have not received periodontal therapy within 6 months. Periodontal pockets with 4-7mm. No antimicrobials for 1 month prior to the study.

Exclusion criteria

Exclusion criteria: Presence of other systemic disorder, genetic disorders, and diseases which will Affect periodontal health. Patients with Acute oral disease. Smokers and tobacco chewers and alcoholics Patient who are allergic to drugs. Pregnant and lactating women. Patients who do not comply to oral hygiene instructions and recall maintenance. Patients who are medically and mentally challenged

Design outcomes

Primary

MeasureTime frame
1. What is the comparative performance of chitosan gels with thermosensitive properties versus those without them in managing periodontal pockets? 2.How do chitosan gels impact the levels of pyruvate kinase (PK) enzyme in saliva?Timepoint: BASELINE TO 6 MONTHS

Secondary

MeasureTime frame
How effective are chitosan gels on clinical parameters of moderate to severe periodontitis ? Timepoint: BASELINE TO 6 MONTHS

Countries

India

Contacts

Public ContactDr. Vinnakota Aparna

Panineeya Mahavidyala Institute of Dental Sciences and Research Centre

surya.prasanna@yahoo.com9440387830

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026