Health Condition 1: G80- Cerebral palsy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Group 1:Children diagnosed with Cerebral Palsy as per American Academy of Neurology Criteria(accompanied by primary caregiver Group 2:Children attending the OPD for minor illness matched for age (+-6 months) and sex or siblings of children admitted in paediatrics wards
Exclusion criteria
Exclusion criteria: Group 1. Children with known diagnosis of metabolic bone disorders Children on bisphosphonates /more than 2 weeks of steroids Children who have received megadoses of Vitamin D in the last 3 months. Children on ketogenic diet Children after onset of puberty Children with documented fractures in last 12 months Group2 Children after onset of puberty Children with documented fractures in the last 12 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean/median serum levels of TP1NP(Total procollagen type 1 N terminal propeptide) and Beta-cross laps(B-CTX) levels in ambulatory and non-ambulatory children with cerebral Palsy and age and sex matched apparently healthy populationTimepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference in Mean/Median serum levels of other bone metabolism markers(vitamin D/ PTH: para thyroid hormone/ALP: alkaline phosphatase/serum calcium/serum phosphate/osteocalcin) in children with cerebral Palsy & age & sex matched, apparently healthy populationTimepoint: Baseline;Mean difference in dietary intake of calcium in these two groupsTimepoint: | — |
Countries
India
Contacts
Maulana Azad Medical College