Driving pressure guided positive end expiratory pressure (PEEP) vs fixed PEEP in preventing lung collapse.

Comparison of driving pressure guided optimum versus fixed positive end expiratory pressure to prevent atelectasis of lungs in paediatric laparoscopic abdominal surgery cases a prospective randomised double blind study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/095058

Enrollment

Registered

2025-09-18

Start date

Unknown

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K40-K46- Hernia Health Condition 2: K35-K38- Diseases of appendix Health Condition 3: K80-K87- Disorders of gallbladder, biliary tract and pancreas Health Condition 4: N40-N53- Diseases of male genital organs Health Condition 5: K55-K64- Other diseases of intestines

Interventions

Intervention1: Driving pressure guided Optimum PEEP: In volume controlled mode, tidal volume of 6-7ml/kg, and PEEP of 4cmH2O will be set after intubation. Incremental PEEP protocol will be used starti

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA GRADE 1 and 2 undergoing elective laparoscopic abdominal surgeries with informed consent

Exclusion criteria

Exclusion criteria: Patient parents refusal Pre-existing lung disease Chest wall or thoracic spine deformity Pre-existing significant cardiac, renal and hepatic diseases Previous history of thoracic surgery

Design outcomes

Primary

Measure	Time frame
To identify whether driving pressure guided optimum PEEP can reduce the magnitude of post-operative (30 minutes after extubation) lung atelectasis as compared to a fixed PEEP assessed by change in modified lung score.Timepoint: Lung ultrasound at baseline, before pneumoperitoneum, after deflation of pneumoperitoneum and before extubation, 30 minutes after shifting to PACU	—

Secondary

Measure	Time frame
To compare post-operative pulmonary complication within three days of surgeryTimepoint: Post-operative;To compare requirement of supplemental oxygen to maintain oxygen saturation more than 94% in postoperative period and on first postoperative dayTimepoint: Post-operative	—

Countries

India

Contacts

Public ContactDr Mayank Kumar

AIIMS Raipur

mayanksonupmch@gmail.com9971760416

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026