Health Condition 1: N950- Postmenopausal bleeding
Conditions
Interventions
Intervention1: Oral Melatonin 5 mg tablet: Oral Melatonin 5 mg tablet given at 10 pm on the night before surgery and at 6 am on the day of surgery.
Control Intervention1: Oral Alprazolam 0.25 mg table
Sponsors
Abhirami NP
Eligibility
Inclusion criteria
Inclusion criteria: Female patients aged more than thirty years but less than sixty five years. Patients undergoing elective abdominal hysterectomy. Patients belonging to American Society of Anaesthesiologists physical status class one or two. Height between one hundred fifty centimeter and one hundred seventy centimeter. Body mass index between eighteen and thirty kilogram per square meter.
Exclusion criteria
Exclusion criteria: Patients with contraindications to regional anaesthesia. Patients with mental impairment. Patients with history of chronic pain. Patients with history of psychiatric illness or those taking psychotropic drugs in the past or present. Patients posted for emergency surgeries.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preoperative oral melatonin significantly reduces postoperative pain scores compared to those receiving oral aprazolam as premedication in patients undergoing elective abdominal hysterectomy.Timepoint: 6,12,24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative oral melatonin reduces anxiety more compared to preoperative oral alprazolam.Timepoint: 30 minutes before surgery;Preoperative oral melatonin providesbetter sedation than oral alprazolam.Timepoint: 6,12 hours | — |
Countries
India
Contacts
Public ContactAbhirami NP
Government Medical College Kozhikode
Outcome results
None listed