Health Condition 1: M17- Osteoarthritis of knee
Conditions
Interventions
None listed
Sponsors
SAVA Healthcare Pvt Ltd
Eligibility
Inclusion criteria
Inclusion criteria: Age greater than or equal to 50 Years Diagnosed with primary knee OA as per ACR criteria ACR Functional Status Class I, II, or III Willing to give informed consent Diagnostic criteria as per ACR (American College of Rhuematology) Knee pain plus any three of the following: Age greater than or equal to 50 years Morning stiffness less than 30 minutes Crepitus Bony tenderness Bony enlargement No palpable warmth
Exclusion criteria
Exclusion criteria: Radiographic Grade greater than or equal to 3 OA (Kellgren-Lawrence classification) Significant knee trauma or arthroscopy in past 1 year History of knee joint replacement BMI greater than or equal to 30 kg per m Intra-articular corticosteroids or hyaluronic acid in the last month Use of corticosteroids in last month History of rheumatoid arthritis, psoriatic arthritis, or any inflammatory arthritis Liver enzymes greater than 3 normal, or serum creatinine greater than 1.2 mg% Active or prior malignancy Known hypersensitivity to study drugs Any condition that may affect safety or compliance (as per the investigator s opinion)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in Clinical Symptoms of Knee OA Improvement in WOMAC Index Score Improvement in Numeric Pain Rating Scale (NPRS) Improvement in inflammatory and degenerative markers Improvement in health-related quality of life (SF-12) Reduction in Rescue Analgesic useTimepoint: Follow up on Days 30th, 60th, 90th, 120th | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactDr MADHAVI MAHAJAN
BVDU COLLEGE OF AYURVED AND HOSPITAL,
Outcome results
None listed