FindTrial
Sign In

Studying the ability of a new score (Delta POX-HR) to predict need for invasive oxygen therapy in ICU patients on High Flow Nasal Cannula (HFNC), suffering from Trauma.

Ability of Delta POX-HR index score to predict HFNC outcome in trauma patients with Acute Hypoxemic Respiratory Failure (AHRF): A Prospective Observational Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/09/095041
Enrollment
207
Registered
2025-09-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J960- Acute respiratory failure

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Babita Gupta
Lead Sponsor
Department of Anesthesiology Pain Medicine and Critical Care
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: All adult patients aged 18-65 years, admitted in ICU requiring HFNC for AHRF.

Exclusion criteria

Exclusion criteria: 1) Patients requiring intubation for surgical procedures. 2) Patients receiving HFNC therapy after extubation. 3) Patients with DNR orders. 4) Patients requiring readmission to ICU and initiated on HFNC therapy. 5) Patients who may require urgent intubation within two hours after HFNC initiation or require ET intubation. 6) Patients who are receiving NIV and HFNC alternately. 7) Refusal of Patient or Patient’s attendants (in case patient is unable to) to consent to study. 8) Patients on Beta-blockers, Beta agonists, alpha-2 agonists, amiodarone, CCB, digoxin or alpha-2 agonists.

Design outcomes

Primary

MeasureTime frame
Escalation of HFNC (to NIV / Intubation defined as HFNC Failure) predicted using Delta POX-HR at 3 hours Timepoint: 3 hours after HFNC Initiation—

Secondary

MeasureTime frame
Escalation of HFNC (to NIV / Intubation defined as HFNC Failure) predicted using Delta POX-HR at 12 hours Timepoint: 12 hours after HFNC Initiation;Escalation of HFNC (to NIV / Intubation defined as HFNC Failure) predicted using Delta POX-HR at 24 hours Timepoint: 24 hours after HFNC Initiation;Escalation of HFNC (to NIV / Intubation defined as HFNC Failure) predicted using Delta POX-HR at 48 hours Timepoint: 48 hours after HFNC Initiation—

Countries

India

Contacts

Public ContactYash Mishra

Department of Anaesthesiology, Pain Medicine and Critical Care, AIIMS

drbabitagupta@hotmail.com9818302776

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026