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Comparison of different doses of Dexmedetomidine for the treatment of shivering in patients undergoing C-section under Spinal Anaesthesia

Comparative Evaluation of different doses of Dexmedetomidine for the treatment of shivering in parturients undergoing Caesarean section under Subarachnoid block - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/095027
Enrollment
123
Registered
2025-09-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: i.v Dexmedetomidine o.3 microgram/kg: We are trying to evaluate 0.3mcg/kg dose of inj. Dexmedetomidine to treat shivering in patients during c-section under spinal anaesthesia. We will

Sponsors

VMMC and Safdarjung Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade 2 gestational age more than equal to 37 weeks scheduled for elective c-section under subarachnoid block who present with shivering.

Exclusion criteria

Exclusion criteria: Parturients with Height less than 150cm or more than 170 cm Initial body temperature of more than 38 degree Celsius or less than 36 degrees Celsius. Chronic user of adrenergic receptor blockers or calcium channel blockers. Known history of alcohol or substance abuse or post-partum hemorrhage

Design outcomes

Primary

MeasureTime frame
Shivering scores in groups with different dexmedetomidine doses Timepoint: Reduction of Shivering scores within 10 minutes in groups with different dexmedetomidine doses assessed by Crossley Et al shivering score.

Secondary

MeasureTime frame
1.Time taken for reduction of shivering score less than one after inj. dexmedetomidine 2.Duration of anti shivering effect. 3.Measurement of MAP,HR,SPO2,temperature at different time intervals. 4. Assessment of sedation. 5. Dose of rescue anti shivering drug.Timepoint: Assessment of sedation with Ramsay Sedation Score every 5 minutes intervals at 5 minutes after dexmedetomidine injections for total 45 minutes.

Countries

India

Contacts

Public ContactDrDharam Singh Meena

Vardhman Mahavir Medical College and Safdarjung Hospital

dharams_meena@yahoo.com09910277131

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026