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Studying Blood Vessel Changes and Inflammation in People with Type 1 Diabetes and Their Link with Blood Sugar Levels

Nailfold Capillaroscopy, HbA1c, IL-6, and IL-35 in Type 1 Diabetes : A Cross- Sectional Analysis of Microvascular Involvement - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/09/095014
Enrollment
60
Registered
2025-09-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E108- Type 1 diabetes mellitus with unspecified complications

Interventions

Intervention1: Nil: Nil

Sponsors

Chitwan Kaur Ghuman
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosed with T1DM for at least six months. Age: 05-20 years. No history of other vascular diseases.

Exclusion criteria

Exclusion criteria: Smoking, hypertension (HTN), Type 2 diabetes, Any connective tissue disease, History of organ dysfunction (heart, liver, kidney), Nail infections, Aesthetic treatment of nails. Prior or current use of immunosuppressive drugs/ NSAIDS. Presence of acute infections at the time of sampling. Did not give consent.

Design outcomes

Primary

MeasureTime frame
To evaluate the role of NFC in detecting early microvascular changes in T1DM Timepoint: 12 months—

Secondary

MeasureTime frame
To investigate the role of cytokine biomarkers (IL-6 & 35) in microvascular changes. To establish relationship between HbA1c levels & capillary anatomy as markers of glycemic control & microvascular status. To correlate fundus imaging findings & renal markers with NFC.Timepoint: 12 months—

Countries

India

Contacts

Public ContactChitwan Kaur Ghuman

JSS Medical College

ashwinipk@jssuni.edu.in9886379361

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026