Combining Ayurvedic & Conventional Care for Better Management of Knee Osteoarthritis

Holistic Healing for Knee Osteoarthritis: Comparing Integrated, Standard Medical, and Ayurvedic Care - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/094919

Enrollment

300

Registered

2025-09-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Age between 30 and 65 years, including males and females both. Diagnosis of primary osteoarthritis (OA) affecting at least one knee joint. Kellgren-Lawrence (KL) grading of 1 or 2, indicating mild to moderate OA severity. Baseline Numeric Rating Scale (NRS) score of more than or equal to 5 out of 10, indicating moderate to severe pain intensity.

Exclusion criteria

Exclusion criteria: Secondary arthritis due to systemic inflammatory arthritis. History of post-traumatic knee osteoarthritis. Previous total knee replacement (TKR) surgery. Recent corticosteroid use for knee-related conditions. Prior intra-articular viscosupplementation treatment. Allergy to allopathic and Ayurvedic medications used in the study. Concomitant skin disease at the application site of any study intervention.

Design outcomes

Primary

Measure	Time frame
The study is expected to demonstrate that integrated home-based care could be a feasible alternative in terms of pain reduction, functional mobility, and quality of life for early OA knee patients, with improved gait kinematics and positive changes in epigenetic and biochemical markers, compared to standard medical and conventional ayurvedic treatments.Timepoint: pain severity assessment ,functional assessment ,joint inflamation will be recorded at baseline,4,8,12,16,20,24 WEEKS, Gait Analysis -baseline,12 & 24 weeks,Biochemical Analysis and Epigenetic analysis -baseline and 24 weeks	—

Measure

Time frame

The study is expected to demonstrate that integrated home-based care could be a feasible alternative in terms of pain reduction, functional mobility, and quality of life for early OA knee patients, with improved gait kinematics and positive changes in epigenetic and biochemical markers, compared to standard medical and conventional ayurvedic treatments.Timepoint: pain severity assessment ,functional assessment ,joint inflamation will be recorded at baseline,4,8,12,16,20,24 WEEKS, Gait Analysis -baseline,12 & 24 weeks,Biochemical Analysis and Epigenetic analysis -baseline and 24 weeks

—

Secondary

Measure	Time frame
NilTimepoint:	—

Countries

India

Contacts

Public ContactNitesh Manohar Gonnade

AIIMS, Jodhpur

drniteshgonnade9@gmail.com9530199967

Outcome results