Comparison of Trichloroacetic Acid Peel and Glycolic Acid Peel in the Treatment of Acanthosis Nigricans

Efficacy of 15% Trichloroacetic Acid Peel versus 35% Glycolic Acid Peel in Acanthosis Nigricans At a Tertiary Care Center in Central Karnataka - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/094913

Enrollment

Registered

2025-09-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 15% Trichloroacetic acid peel: 15% Trichloroacetic acid peel applied at 2-weekly intervals for 6 sessions over affected areas of acanthosis nigricans. Control Intervention1: 35% Glycoli

Eligibility

Inclusion criteria

Inclusion criteria: All adults 18 years and older with a clinical diagnosis of AN affecting the face, neck, or elbow, or any combination of these three, who presented to the dermatology outpatient department and are willing to give consent

Exclusion criteria

Exclusion criteria: Pregnant and lactating females. Hypersensitivity to the peeling agent. Skin infection at the site of AN (herpes, pyoderma, and folliculitis). Individuals prone to keloid formation. History of any topical application in the last 4 weeks

Design outcomes

Primary

Measure	Time frame
Reduction in severity of acanthosis nigricans as assessed by Acanthosis Nigricans Severity Index (ANSI) scoreTimepoint: At baseline, 2,4,6 and 8 weeks after initiation of treatment	—

Secondary

Measure	Time frame
Patient satisfaction assessed by Visual Analogue Scale (VAS).Timepoint: At 12 weeks.	—

Countries

India

Contacts

Public ContactDr Ashwini K Ajjewadermath

JJM Medical College

drhcmangala@gmail.com9886075467

Outcome results