Health Condition 1: J459- Other and unspecified asthma
Conditions
Interventions
Intervention1: Dexamethasone: Dexamethasone in a dosage of 0.3mg/kg/day (Max: 16mg/day)
Frequency: Once daily
Route: Oral
Duration: 2 days
Control Intervention1: Prednisolone: Prednisolone, in a dosag
Sponsors
Government Medical College and Hospital Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: Children between the ages of 2 years to less than 18 years hospitalized with acute exacerbation of asthma.
Exclusion criteria
Exclusion criteria: Life threatening exacerbation requiring PICU admissions. Known hypersensitivity to dexamethasone or prednisolone. Chronic comorbidities (e.g., congenital heart disease, immunodeficiencies). Prior corticosteroid use in the last 30 days Children already enrolled in the study and presenting within 30 days of discharge from hospital.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in mean PRAM scoresTimepoint: Baseline (admission) and day 4 of treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Pediatric Respiratory Assessment Measure, measured 6 hourly till discharge or transfer from emergency departmentTimepoint: 6 hourly till discharge;Length of hospital stayTimepoint: admission to discharge;Incidence of adverse effectsTimepoint: admission to discharge;Unscheduled visits to hospital due to symptoms of exacerbation asthma within 60 days of administration of steroidsTimepoint: discharge to 60 days after discharge;Persistence of symptoms after 7 days of discharge.Timepoint: discharge till 7 days after discharge;Duration of admission in emergency departmentTimepoint: admission to discharge | — |
Countries
India
Contacts
Public ContactDr Pryas Jain
Government medical college, Chandigarh
Outcome results
None listed