How to prevent shivering During Spinal Anaesthesia in Urology Patients: A comparison of three drugs DEXMEDETOMIDINE , DEXAMETHASONE AND MAGNESIUM SULPHATE .

Comparative study of intravenous administration of Dexmedetomidine , Dexamethasone and Magnesium Sulphate in prevention of shivering in urological surgeries done under spinal anaesthesia - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/094895

Enrollment

120

Registered

2025-09-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: DEXMEDETOMIDINE : spinal anaesthesia will be administered following the standard protocol ,after confirming adequate sensory block ( T10 level), dexmedetomidine 0.5 mcg/kg in 100 ml NS

Eligibility

Inclusion criteria

Inclusion criteria: Age: 18-65 years ASA Grading I & II Patients undergoing elective urological surgeries under spinal anaesthesia Both genders

Exclusion criteria

Exclusion criteria: Emergency surgeries Known hypersensitivity to any of the agents used in the study Patients with uncontrolled hypertension, diabetes mellitus, or thyroid disorders Patients with cardiovascular, respiratory, hepatic, or renal impairment ( moderate to severe ) Patients on alpha-adrenergic receptor antagonists, calcium channel blockers, or on chronic steroid therapy Patients with a history of alcohol or drug abuse Patients with psychiatric disorders Non-consenting patients

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of intravenous dexmedetomidine, dexamethasone, and magnesium sulphate for prevention of shivering after spinal anaesthesia in urological surgeries.Timepoint: o Baseline vitals(before spinal anesthesia) o 10 minutes after spinal anesthesia (before drug administration) o Every 10 minutes after drug administration until the end of surgery o At the completion of surgery and 30 minutes post-surgery in the recovery room	—

Measure

Time frame

To compare the efficacy of intravenous dexmedetomidine, dexamethasone, and magnesium sulphate for prevention of shivering after spinal anaesthesia in urological surgeries.Timepoint: o Baseline vitals(before spinal anesthesia) o 10 minutes after spinal anesthesia (before drug administration) o Every 10 minutes after drug administration until the end of surgery o At the completion of surgery and 30 minutes post-surgery in the recovery room

—

Secondary

Measure	Time frame
1. To study the hemodynamic changes with the use of these drugs. 2. To monitor and compare the incidence and severity of side effects/complications with the use of these drugs. 3. To assess the level of sedation associated with each intervention.Timepoint: 0 mins 10 mins 20 mins 30 mins 40 mins 50 mins 60 mins at the end of surgery	—

Countries

India

Contacts

Public ContactArtan Preet Kaur

Adesh Institute of Medical Sciences and Reseach (AIMSR). Bathinda

drmmprao@gmail.com8699943250

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026