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COMPARISON OF POSTOPERATIVE ANALGESIA OF PRE-OPERATIVE ORAL ADMINISTRATION OF VITAMIN C VERSUS PARACETAMOL IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY UNDER GENERAL ANESTHESIA : A COMPARATIVE RANDOMISED PROSPECTIVE STUDY

COMPARISON OF POSTOPERATIVE ANALGESIA OF PRE-OPERATIVE ORAL ADMINISTRATION OF VITAMIN C VERSUS PARACETAMOL IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY UNDER GENERAL ANESTHESIA : A COMPARATIVE RANDOMISED PROSPECTIVE STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/094825
Enrollment
110
Registered
2025-09-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Administration of preoperative oral Vitamin C: Assessment of postoperative pain and sore throat in first 24 hours Control Intervention1: Administration of preoperative oral paracetamol:

Sponsors

JSS Academy of Higher Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status I and II patients Patients undergoing elective laparoscopic cholecystectomy under general anaesthesia

Exclusion criteria

Exclusion criteria: Patients with a history of allergy to tablet vitamin C and paracetamol Pregnant and lactating women Patients with known G6PD deficiency Patients receiving analgesics for any other indication such as cancer pain, chronic pain pathologies Patients who receive injection dexamethasone intra operatively for any other indication

Design outcomes

Primary

MeasureTime frame
To assess and compare the severity of post operative pain in the first 24 hours in patients receiving preoperative oral Vitamin C versus oral paracetamolTimepoint: Assessment of severity of pain at hours 1, 6, 24 post surgery—

Secondary

MeasureTime frame
A. Assessment of time of first rescue B. Number of times rescue analgesic needed C. Severity of sore throatTimepoint: A. Hours post surgery at which first dose of rescue analgesic given B. Total number of rescue medications needed in 24 hours C. Severity of sore throat at hours 1, 6, 24 post surgery—

Countries

India

Contacts

Public ContactDR VYSHNAVI S

JSS ACADEMY OF HIGHER EDUCATION AND RESEARCH

vyshgiri@gmail.com9880110022

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026