Health Condition 1: H470- Disorders of optic nerve, not elsewhere classified
Conditions
Interventions
Intervention1: Oral Prednisolone tablet(Wysolone): starting on 1 mg per kg Prednisone loading dose which will be tapering down by 10mg every 5 days
Control Intervention1: Intravitreal Traimcinolone Ac
Sponsors
Dr Shrutika Laxmikant Pokale
Eligibility
Inclusion criteria
Inclusion criteria: All diagnosed cases of NA-AION, presenting with - A history of sudden painless visual loss and an absence of other ocular, systemic or neurological diseases that might influence or explain the patient s visual symptoms, with Optic disc edema (ODE) RNFL thickness more than 120 measured by spectral domain OCT HFA (30-2 programme)showing altitudinal visual field defect No history of neurologic, systemic or ocular disorder, which could be responsible for ODE and visual impairment must be present. The patient must not have had any treatment for NA-AION prior to our evaluation, There must be a follow-up of 3 months at least to provide enough length of follow-up to obtain valid information in the three treated groups
Exclusion criteria
Exclusion criteria: Patients who had any retinal or optic nerve lesion (Glaucoma/ Vascular diseases or Uveitis) or any other factor (e.g. cataract) which could influence the visual status. NA-AION patients with only background diabetic retinopathy will be included, but those who has active neovascularization, vitreous hemorrhages, traction detachment, DME or other complications influencing the visual acuity or fields will be excluded. Patients who had a diagnosis of glaucoma and visual field loss are excluded; however, those with history of elevated intraocular pressure and on ocular hypotensive therapy, with a documented normal field prior to the onset of NA-AION, are included. Patients with a follow-up of less than 3 months are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual acuity by LogMAR chartTimepoint: 1week,1 month,3month | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual fields by HFATimepoint: 1week,1month,3months;Mean RNFL thickness on OCTTimepoint: 1week,1month,3months | — |
Countries
India
Contacts
Public ContactDr Ashok Kanakamedala
Sankara Eye Hospital,Guntur
Outcome results
None listed