Health Condition 1: N288- Other specified disorders of kidney and ureter
Conditions
Interventions
Intervention1: Using either of the two modes of ventilation under GA for laparoscopic nephrectomy surgeries and arterial sample will be sent at various time points to note the effect of ventilation on
Sponsors
Amrita Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: ASA I,II,III
Exclusion criteria
Exclusion criteria: Obesity with BMI more than 30 Active Smoking Moderate to Severe COPD Emergency Nephrectomy Conversion to open surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effect of two different ventilatory modes i.e pressure control ventilation and volume control ventilation on the PaCO2 to EtCO2 gradient during laparoscopic nephrectomy in lateral decubitus position at T2c time point.Timepoint: T2c time point is 90 minutes after creation of pneumoperitoneum intraop. | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference in alveolar arterial oxygen gradient between two modes.Timepoint: At 8 different time points T1a-10 minutes after induction when patient is hemodynamically stable T1b-10 minutes after placing patient in lateral position & prior to CO2 insufflation T2a-30 minutes during period of pneumoperitoneum T2b-60 minutes during period of pneumoperitoneum T2c-90 minutes during period of pneumoperitoneum T2d-120 minutes during period of pneumoperitoneum T3a-10 minutes after release of pneumoperitoneum T3b-10 minutes after patient is made supine at end of procedure;To compare hemodynamic changes in the two groups.Timepoint: At 8 different time points T1a-10 minutes after induction when patient is hemodynamically stable T1b-10 minutes after placing the patient in lateral position & prior to CO2 insufflation T2a-30 minutes during period of pneumoperitoneum T2b-60 minutes during period of pneumoperitoneum T2c-90 minutes during period of pneumoperitoneum T2d-120 minutes during period of pneumoperitoneum T3a-10 minutes after release of pneumoperitoneum T3b-10 minutes after patient is made supine at end of procedure.;To study the PaCO2 to EtCO2 gradient in different surgical techniques i.e intraperitoneal & retroperitoneal approach.Timepoint: At 8 different time points T1a-10 minutes after induction when patient is hemodynamically stable T1b-10 minutes after placing the patient in lateral position & prior to CO2 insufflation T2a-30 minutes during period of pneumoperitoneum T2b-60 minutes during period of pneumoperitoneum T2c-90 minutes during period of pneumoperitoneum T2d-120 minutes during period of pneumoperitoneum T3a-10 minutes after release of pneumoperitoneum T3b-10 minutes after patient is made supine at end of procedure.;Peak airway pressure & dynamic compliance between two modes of ventilation.Timepoint: At 8 different time points. T1a-10 minutes after induction when patient is hemodynamically stable T1b-10 minutes after placing the patie | — |
Countries
India
Contacts
Public ContactPriyanka Joseph
Amrita Institute of Medicsl Science,Kochi
Outcome results
None listed