Health Condition 1: L00-L99- Diseases of the skin and subcutaneous tissue
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with clinically diagnosed non-segmental vitiligo. Presence of at least 3 vitiligo patches scheduled for NB-UVB phototherapy. One acral (hands/feet/bony prominence) and one non-acral lesion will be selected whenever feasible. Patient provides written informed consent
Exclusion criteria
Exclusion criteria: Patients who used systemic or topical medications for vitiligo in the past 4 weeks or receiving surgical treatment. Patients with other significant dermatoses. Pregnant or breastfeeding women. Patients with history of photosensitizing disorders, sensitivity to phototherapy, or claustrophobia. Uncooperative or unwilling participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Vitiligo Area Scoring Index (VASI) after NB-UVB phototherapy, and correlation of dermoscopic findings with this change in patients with non-segmental vitiligo.Timepoint: Baseline (before starting NB-UVB) 4 weeks of treatment 8 weeks of treatment 12 weeks of treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Correlation of specific dermoscopic patterns (e.g., perifollicular repigmentation, pigment network) with extent of clinical improvement. 2)Access Safety/tolerability of NB-UVBTimepoint: Baseline (before starting NB-UVB) 4 weeks of treatment 8 weeks of treatment 12 weeks of treatment | — |
Countries
India
Contacts
Sawai Man Singh Medical College and hospitals