Skip to content

A Comparative Study of 2 drugs Dexmedetomidine and Nefopam For Treatment Of Intraoperative Shivering in Adult Patients Undergoing Surgery Under Anesthesia

Thermoregulatory Challenges In The Operating Room: Dexmedetomidine Versus Nefopam In The Management Of Intraoperative Shivering- A Comparative Study - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/094745
Enrollment
40
Registered
2025-09-15
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: Both Drugs Are Used For Control Of Intraoperative Shivering. This Study Aims To Compare The Thermoregulatory Effects, Efficacy And Safety Profile Of Both Drugs In Contr

Sponsors

Dr Ambati Santosha Lakshmi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients Undergoing Elective Surgeries Under Regional Anaesthesia.

Exclusion criteria

Exclusion criteria: Known Hypersensitivity To Study Drugs Severe Cardiovascular, Respiratory, Renal, Hepatic And Neurological Diseases. Patients With A Contraindication To Regional Anaesthesia

Design outcomes

Primary

MeasureTime frame
Nefopam is better as compared to dexmedetomidine for control of intraoperative shivering under spinal anesthesia due to its rapid onset, higher response rate, no sedation, lesser hemodynamic alterations, lesser requirements of rescue analgesics & lesser costs.Timepoint: Baseline

Secondary

MeasureTime frame
Nefopam is better as compared to dexmedetomidine for control of intraoperative shivering under spinal anesthesia due to its rapid onset, higher response rate, no sedation, lesser hemodynamic alterations, lesser requirements of rescue analgesics & lesser costs.Timepoint: Baseline

Countries

India

Contacts

Public ContactDr Ambati Santosha Lakshmi

Gitam Institute Of Medical Sciences And Research

sambati2@gitam.edu9440532547

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026