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Zinc for improving taste in breast cancer chemotherapy

Topical Zinc sulphate for chemotherapy-induced dysgeusia among breast cancer patients receiving Chemotherapy:- Pilot study patients receiving Chemotherapy- Pilot study - ZnTC

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/094739
Enrollment
20
Registered
2025-09-15
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50- Malignant neoplasm of breast

Interventions

Intervention1: Topical Zinc Sulfate: The dispersible zinc sulphate tablet 50 mg will be reconstituted in distilled water (50 mg in 10 ml) Control Intervention1: NA: NA

Sponsors

Dr Mirunalini R
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients with breast cancer planned for curative intent therapy (neoadjuvant or adjuvant ) with epirubicin and cyclophosphamide agents during first cycle

Exclusion criteria

Exclusion criteria: 1. Patients who had received zinc preparations within the last two weeks of enrolment 2. Known hypersensitivity to the drug 3. Known psychiatric disorder 4. Regular alcohol intake (3 or more drinks equivalent of 45 ml of liquor per week)

Design outcomes

Primary

MeasureTime frame
Change in taste perception by taste acuity method Change in CiTAS scoreTimepoint: Baseline and two weeks

Secondary

MeasureTime frame
Adverse drug reaction to Topical ZincTimepoint: Over two weeks

Countries

India

Contacts

Public ContactMirunalini R

JIPMER, Puducherry

pg1980@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026