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Dexmedetomidine Nebulization to Improve Recovery After CABG Surgery

An Observational Study on Effect of Dexmedetomidine Nebulization on postoperative Quality of Recovery in patients undergoing off-pump Coronary Artery Bypass Grafting - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/094724
Enrollment
108
Registered
2025-09-12
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I00-I99- Diseases of the circulatory system

Interventions

Intervention1: Dexmedetomidine Nebulization: Dexmedetomidine 1 mcg/kg in 5 ml NS every 12th hourly. Intervention2: Dexmedetomidine Nebulization: Dexmedetomidine 1 mcg/kg in 5ml NS Intervention3: Dexme

Sponsors

Non-Sponsored Academic Project
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Elective OPCABG patients. Age 40?75 years. ASA II, III patients. Consent to participate.

Exclusion criteria

Exclusion criteria: 1. Emergency surgery. 2. Severe hepatic or renal dysfunction. 3. AV block (Grade II/III) without pacemaker. 4. Chronic use of sedatives/opioids. 5. Allergy to dexmedetomidine. 6. Pre-existing psychiatric or neurological illness.

Design outcomes

Primary

MeasureTime frame
Postoperative Quality of Recovery Score using the QoR-40 Questionnaire at 24 and 48 hours post-extubation.Timepoint: Postoperative Quality of Recovery Score using the QoR-40 Questionnaire at 24 and 48 hours post-extubation.—

Secondary

MeasureTime frame
?Hemodynamic parameters (HR, BP) at 6, 12, 18, 24 hours ?Postoperative opioid consumption in first 24 hours. ?ICU and hospital length of stay. ?Adverse events: bradycardia, hypotension, desaturation. Timepoint: 6, 12, 18, 24 hours—

Countries

India

Contacts

Public ContactDr Arya K S

Fortis Hospitals Limited

priyankajoshi1@gmail.com9870412128

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026