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Role of resveratrol in oral Premalignant diseases

Therapeutic potential of Natural polyphenol-Resveratrol in Premalignant oral lesions-A Randomised Controlled Study? - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/094674
Enrollment
60
Registered
2025-09-12
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1 Adults aged 18?70 years 2 Histologically confirmed OPLs (e.g.leukoplakia, oral epithelial dysplasia) 3 Lesion size should be more than or equal to 1cm 4 No prior treatment for the current lesion. 5 Willingness to comply with study procedures and provide informed consent.

Exclusion criteria

Exclusion criteria: 1 Malignant oral lesions 2 Severe systemic conditions or immunocompromised status 3 Pregnancy or lactation 4 Known hypersensitivity to resveratrol 5 Concurrent use of other chemopreventive agents.

Design outcomes

Primary

MeasureTime frame
? Change in lesion size and clinical appearance. ? Histopathological assessment of dysplasia grade. Timepoint: Duration of study - 12 months—

Secondary

MeasureTime frame
? Patient-reported pain & discomfort scores. ? Incidence of adverse events. ? Biomarker analysis for molecular mechanismsTimepoint: Duration of study -12 months—

Countries

India

Contacts

Public ContactJiwyansh Sachdeva

Manav rachna dental college

Sachdevajiwyansh26@gmail.com08766338074

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026