comparing the pain on injection and pain during root canal treatment on giving normal, laser and cold injection.

comparative evaluation of the effects of photobiomodulation and topical cooling of injection site, as pre-anesthetic modalities during the administration of local anesthesia in maxillary molars with symptomatic irreversible pulpitis- A randomized control trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/094657

Enrollment

Registered

2025-09-12

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: photobiomodulation & 2% lignocaine HCL with 1:80,000 epinephrine: one time intervention by Photobiomodulation with diode laser (980nm) for 20 secs with low level laser tip over the inje

Eligibility

Inclusion criteria

Inclusion criteria: Patients with good health in the age group of 20-40 years. Patients with symptomatic irreversible pulpitis of maxillary molars. Patients with preoperative pain score greater than 54mm as measured on HP-VAS scale.

Exclusion criteria

Exclusion criteria: Individuals with systemic and mental illness. Individuals with known allergy or contraindication to lignocaine. Pregnant and lactating mothers. Individuals who have taken analgesics 12hrs before endodontic procedure. Individuals under barbiturates and benzodiazepine medication. Presence of chronic endodontic lesions in relation to the tooth.

Design outcomes

Primary

Measure	Time frame
Evaluate the onset, anesthetic efficacy and injection pain during administration of cold anesthesia and photobiomodulation.Timepoint: Evaluate the onset, anesthetic efficacy and injection pain during administration of cold local anesthesia and photobiomdulation at the baseline.	—

Secondary

Measure	Time frame
Intergroup comparison of the effects of the anesthesia.Timepoint: Compare the effect of anesthesia in males & females at the baseline.	—

Countries

India

Contacts

Public ContactDr GIRISH T N

Coorg institute of dental sciences

nhitesh1369@gmail.com9538935359

Outcome results