Health Condition 1: I10- Essential (primary) hypertension
Conditions
Interventions
Intervention1: Telmisartan plus hydrochlorothiazide with zinc sulphate: Telmisartan 40 mg and Hydrochlorothiazide
12.5 mg once daily in the morning at for three month + Zinc 20 mg elemental zinc once
Sponsors
Mini Sharma
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged between 18 to 65 years Newly diagnosed case of Grade 1 primary hypertension Systolic BP 140 to 159 mm of Hg DBP 90 to 99 mm Hg Patient is willing to come for follow up till 12 weeks Patient is willing to give informed written consent
Exclusion criteria
Exclusion criteria: Patient suffering with Stage 2 or stage 3 primary hypertension Patient suffering with diagnosed secondary hypertension Patients have contraindication or allergic to Zinc, Telmisartan or Hydrochlorothiazide Patient giving history of taking mineral supplement in last 3 month before enrolment Patient having history of ischemic heart disease, stroke, congestive heart failure, clinically significant arrhythmia or conduction disorders, diagnosed end stage renal disease, abnormal liver function or critically ill patient Systolic Blood pressure difference in both arms more than 10 mmHg Pregnant female Lactating mother
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Change in systolic blood pressure (SBP) from baseline to 12 weeks. 2. Change in diastolic blood pressure (DBP) from baseline to 12 weeks.Timepoint: All the patients will be asked to come for follow-up at 4, and 8- and 12-weeks post-treatment and patients will be evaluated thoroughly for the efficacy, and safety parameters at each visit. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Change in quality of life from baseline to 12 weeks. 2) Incidence, type, causality, preventability and severity of adverse effects in both the group.Timepoint: 1)Quality of life will be evaluated at baseline and 12th week. 2)Any adverse effect will be evaluated and reported during study duration from baseline till 12 weeks. | — |
Countries
India
Contacts
Public ContactMini Sharma
Outcome results
None listed