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Association between Mean perfusion pressure and Acute kidney injury in Septic Shock: A Cohort Study

Association between Mean perfusion pressure and Acute kidney injury in Septic Shock: A Cohort Study - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/09/094573
Enrollment
200
Registered
2025-09-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I998- Other disorder of circulatory system

Interventions

Intervention1: Nil: Nil Intervention2: nil: nil Control Intervention1: nil: nil

Sponsors

AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients aged 18-75 years admitted to ICU with sepsis as per Sepsis-3 criteria and shock

Exclusion criteria

Exclusion criteria: Patient refusal to enroll to the study Pregnant patients Patients who are already a known case of CKD stage 3 and above Patient diagnosed with AKI stage 3 as per KDIGO criteria Patients with raised intra-abdominal pressure

Design outcomes

Primary

MeasureTime frame
Occurrence of AKI will be measured by Serum Creatinine levels and urine output as per KDIGO criteria for AKITimepoint: Hospital discharge or day 30 whichever is earlier—

Secondary

MeasureTime frame
The trajectory of mean perfusion pressure with daily SOFA scoresTimepoint: day 3;Association of MPP trajectory with mortalityTimepoint: day 30;Association between trajectories of MPP & AKITimepoint: day 3;Association between MPP & RRT free daysTimepoint: day 30;Association between MPP & lactate clearance duringTimepoint: 72hrs;Association between MPP & cumulative fluid balanceTimepoint: day 3—

Countries

India

Contacts

Public ContactKaushik D S

AIIMS New Delhi

bhattacharjee.sulagna85@gmail.com9818212531

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026