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A study to compare how long muscle strength takes to return after extubation when Atracurium is used in Laparoscopic and open abdominal surgery using Train of Four monitoring

A prospective observational study to compare neuromuscular blockade recovery time with Train of Four after extubation when Atracurium is used as muscle relaxant In Laparoscopic versus open abdominal surgery - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/09/094550
Enrollment
54
Registered
2025-09-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: NIL: NIL

Sponsors

Dr Ibrahim khan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patient undergoing laparoscopic and open abdominal surgeries patient categories under American society of Anesthesiologist(ASA) Grade 1 and 2

Exclusion criteria

Exclusion criteria: patient with pre-existing Asthma, chronic bronchitis, Allergic rhinitis patient having hypersensitivity to Atracurium patient not willing to participate in the study

Design outcomes

Primary

MeasureTime frame
Comparison of Neuromuscular Blockade Recovery Time Using Train of Four Monitoring After Extubation with Atracurium in Laparoscopic versus Open Abdominal surgeryTimepoint: Train of Four monitoring post extubation every 5min till TOF ratio 0.9—

Secondary

MeasureTime frame
to study spontaneous recovery time from last dose of Atracurium to appearance of curare notch To compare the ABG parameters in both groups at the beginning of reversalTimepoint: intra-operative hemodynamic assessment every 15min till the last dose Atracurium to time taken to achieve TOF 0.9 after extubation—

Countries

India

Contacts

Public ContactDr Ibrahim Khan

Bharati vidyapeeth deemed to be university dhankawadi pune,

sarojini.bobde@gmail.com9822914122

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026