Comparison between Metoclopramide and Lignocaine,to reduce pain during propofol induction.

Efficacy of Metoclopramide versus Lignocaine in reducing pain on propofol induction: A randomized controlled trial - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/094527

Enrollment

158

Registered

2025-09-10

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Metoclopramide: Group A will be receiving 2ml of 10 mg of metoclopramide intravenously over 10 seconds Control Intervention1: Lignocaine: Group B will be receiving 2ml of 40 mg lignoca

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients posted for elective surgeries under general anaesthesia 2.American Society of Anaesthesiologists(ASA) physical status 1 and 2 3.18 guage cannula on dorsum of hand

Exclusion criteria

Exclusion criteria: 1.Pregnant females 2. Patients posted for emergency procedures 3.Patients allergic to study drugs 4.Patients requiring rapid sequence intubation 5.Patients with extrapyramidal symptoms

Design outcomes

Primary

Measure	Time frame
To evaluate for reduction of pain on propofol injection with metoclopramide versus lignocaine as pretreatment, using verbal rating scaleTimepoint: 15 seconds	—

Secondary

Measure	Time frame
To observe for adverse effects of the study drugs like itching & swelling, at the site of administration.Timepoint: Patients will be followed up to 6 hours.	—

Countries

India

Contacts

Public ContactDr Manoj Kumar Muni

Kalinga Institute of Medical Sciences

manoj.muni@kims.ac.in7853940106

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026