Comparative study of ultrasound guided analgesic block injection vs local infiltration analgesia for postoperative pain relief after total knee arthroplasty

Comparison of ultrasound guided dual subsartorial block and local infiltration analgesia for postoperative analgesia after total knee arthroplasty - A randomized comparative study - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/094504

Enrollment

Registered

2025-09-10

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: GROUP A - DUAL SUBSARTORIAL BLOCK: Group A will receive an ultrasound-guided Dual Subsartorial Block (DSB) performed by an experienced anesthesiologist (with over 5 years of experience

Eligibility

Inclusion criteria

Inclusion criteria: 1.)Patients belonging American Society of Anesthesiologists (ASA) physical status of I-III. 2.)Patients aged 30?85 of either sex.

Exclusion criteria

Exclusion criteria: 1.)Body mass index (BMI) greater than 35 kg/m2 2.)Severe valgus deformity 3.)Acute/chronic kidney disease 4.)Operative limb neuropathy 5.)Known allergies to local anesthetic agent.

Design outcomes

Primary

Measure	Time frame
To measure the effect of ultrasound guided dual subsartorial block on postoperative analgesia during the first 24hrs in comparison to periarticular infiltration among patients undergoing total knee arthroplasty under spinal anesthesiaTimepoint: VAS, to measure pain intensity in both the groups in first 24 hrs. Time for first rescue analgesia and total dose of rescue analgesia Quadriceps strength Quality of recovery using QOR ? 15 scale Adverse effects	—

Measure

Time frame

To measure the effect of ultrasound guided dual subsartorial block on postoperative analgesia during the first 24hrs in comparison to periarticular infiltration among patients undergoing total knee arthroplasty under spinal anesthesiaTimepoint: VAS, to measure pain intensity in both the groups in first 24 hrs. Time for first rescue analgesia and total dose of rescue analgesia Quadriceps strength Quality of recovery using QOR ? 15 scale Adverse effects

—

Secondary

Measure	Time frame
To compare the time duration for requirement of first rescue analgesia. To compare the total number of breakthrough analgesics administered during the initial 24-hour postoperative period. To compare the quadriceps strength by measuring the total ambulation distance & the degree of active knee extension within the first 24 hours postoperatively. To determine the quality of recovery using QOR ? 15 scale after 24 hrs of surgery in both the groups. To record any adverse effects, such as nausea, vomiting, buckling, deep vein thrombosis, wound infection.Timepoint: AFTER 24 HOURS OF SURGERY	—

Measure

Time frame

To compare the time duration for requirement of first rescue analgesia. To compare the total number of breakthrough analgesics administered during the initial 24-hour postoperative period. To compare the quadriceps strength by measuring the total ambulation distance & the degree of active knee extension within the first 24 hours postoperatively. To determine the quality of recovery using QOR ? 15 scale after 24 hrs of surgery in both the groups. To record any adverse effects, such as nausea, vomiting, buckling, deep vein thrombosis, wound infection.Timepoint: AFTER 24 HOURS OF SURGERY

—

Countries

India

Contacts

Public ContactDr SHYAM SUNDER

Pondicherry institute of medical sciences

shyam.arun90@gmail.com8056194019

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026