Health Condition 1: T885- Other complications of anesthesia
Conditions
Interventions
Intervention1: Inj. Sugammadex in fixed single dose of 200mg by intravenous route.: Inj. Sugammadex is given at a fixed single dose of 200mg by slow intravenous infusion in 100ml normal saline over 5
Sponsors
ESIC Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.19-55 years of age of both sexes. 2.A BMI 20-30 kg/m2. 3.Patient belonging to ASA Physical status I and II. 4.Scheduled for elective surgery with expectant duration greater than 120 minutes under general anesthesia with written informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with contraindication to sugammadex. 2.Patients who are pregnant. 3.Neuromuscular disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the time taken to achieve a normalized TOF ratio 0.9 between recommended dose and fixed dose of suggamadex in reversing moderate neuromuscular blockade.Timepoint: Initial point - Administration of sugammadex on day of surgery after completion of surgical procedure. Final point- Time at which a normalized TOF ratio of 0.9 is achieved on day of surgery after administration of sugammadex. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess time taken from sugammadex administration to fowllowing points (1)spontaneous respiration (2)response to verbal commands (3)motor control (4)extubation (5)recovery time (sugammadex to extubation) Timepoint: On day of surgery after completion of surgical procedure.;To assess advere events & their management in both dosing strategies.Timepoint: On day of surgery after completion of surgical procedure | — |
Countries
India
Contacts
Public ContactM P Manu Pradeep
ESIC Medical College and Hospital
Outcome results
None listed