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Comparison of safety and technique between portal vein embolization via liver and portal vein embolization via liver performed for liver growth before liver resection

Comparison of safety and technical parameters between transhepatic (TH-PVE) and transsplenic (TS-PVE) portal vein embolization for future liver remnant (FLR) augmentation before hepatectomy: A randomized controlled trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/094450
Enrollment
34
Registered
2025-09-09
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere Health Condition 2: K77- Liver disorders in diseases classified elsewhere

Interventions

Intervention1: Portal vein embolization via transsplenic route : Transsplenic PVE (TS-PVE): All the transsplenic portal vein embolization will be performed with patient lying supine and operator stand

Sponsors

Dr Anu Thakur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients with inadequate FLR planned for portal vein embolization before major liver resections

Exclusion criteria

Exclusion criteria: 1. Patients denying consent 2. Locally unresectable disease 3. Distant metastasis 4. Child Pugh B and C cirrhotic patients 5. Clinically significant portal hypertension 6. Extensive intrahepatic portosystemic shunts 7. Tumor thrombus extending into portal vein 8. Women during pregnancy or breastfeeding.

Design outcomes

Primary

MeasureTime frame
To compare the procedure-related major and minor complications between TH-PVE and TS-PVE To compare the procedural technique-related parameters between TH-PVE and TS-PVE Timepoint: With in 30 days of portal vein embolization At the time of portal vein embolization procedure—

Secondary

MeasureTime frame
To compare the degree of hypertrophy of the future liver remnant (FLR)following PVE, measured as percentage increase in FLR volume using CT volumetric imagingTimepoint: At 4-5 wks post portal vein embolization;To compare the procedural challenges (if any) during hepatectomy between the TH-PVE and TS-PVE groupsTimepoint: At the time of hepatectomy—

Countries

India

Contacts

Public ContactDr Ranjan Kumar Patel

AIIMS Bhubaneswar

ranjanair1@gmail.com8851228221

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026