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A study in patients undergoing surgery with general anaesthesia to compare two doses of dexmedetomidine and their effects on blood pressure, heart rate, breathing, oxygen levels, sleepiness and amount of anaesthesia required.

A comparative study to evaluate effect of two doses of dexmedetomidine on hemodynamic changes, sedation score and requirement of propofol in patients undergoing surgery under general anaesthesia in a tertiary care hospital. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/094421
Enrollment
150
Registered
2025-09-08
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z518- Encounter for other specified aftercare

Interventions

Intervention1: Dexmedetomidine: 1.0 Microgram/Kg. Single dose. Intravenous as a preanesthetic agent. Intervention2: Dexmedetomidine: 0.5 Microgram/Kg. Single dose. Intravenous as a preanesthetic agent

Sponsors

BHATT JAINEEL DEVANG
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients undergoing elective surgeries under general anaesthesia(GA). 2.ASA(American Society of Anaesthesiologists) classification grade I or II.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
1.To compare the effects of two doses of dexmedetomidine (0.5 ?g/kg and 1.0 ?g/kg) on hemodynamic changes in patients undergoing surgery. 2.To study and compare the sedation score with two different dose of dexmedetomidine (0.5 ?g/kg and 1.0 ?g/kg). 3.To study requirement of propofol in patients according to Dexmedetomidine dose.Timepoint: 1. Baseline 2. 10 minutes after Dexmedetomidine administration 3. Immediately after induction 4. Immediately after intubation 5. 1 minute after intubation 6. 5 minutes after intubation 7. 10 minutes after intubation—

Secondary

MeasureTime frame
1.To study side effects related to dexmedetomidine if any.Timepoint: 1. Baseline 2. 10 minutes after Dexmedetomidine administration. 3. Immediately after induction 4. Immediately after intubation 5. 1 minute after intubation 6. 5 minutes after intubation 7. 10 minutes after intubation—

Countries

India

Contacts

Public ContactDR VIPUL CHAUDHARI

GCS MEDICAL COLLEGE, HOSPITAL AND RESEARCH CENTRE

drvip79@yahoo.co.in9825444336

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026