Check clinical efficacy of two different doses of intranasal nitroglycerine spray to attenuation of haemodynamic stress response to pneumoperitoneum in laparoscopic surgeries A prospective randomised study

A Prospective Randomised Study to Evaluate the Efficacy of Two Different Doses of Intranasal Nitroglycerine Spray in Attenuating Haemodynamic Stress Response to Pneumoperitoneum during Laparoscopic Surgeries - No

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/094367

Enrollment

Registered

2025-09-08

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil

Eligibility

Inclusion criteria

Inclusion criteria: all adult patients of either 18 to 65 years Here a suitable Inclusion Criteria section for my trial in CTRI formet Inclusion Criteria 1. Adult patients aged 18 to 65 years. 2. ASA Physical Status I?II. 3. Scheduled for elective laparoscopic abdominal surgery ( cholecystectomy appendicectomy diagnostic laparoscopy) under general anaesthesia. 4. Duration of surgery expected to be less than 2 hours. 5. Ability to provide written informed consent.

Exclusion criteria

Exclusion criteria: patient refusal patient with known allergies to study medication patient with uncontrolled hypertension perioperative bradycardia (heart and renal disease) patient on chronic opioid or alpha2-adrenergic agonist or antagonist therapy pregnant or lactating

Design outcomes

Primary

Measure	Time frame
Outcome Measure: Change in haemodynamic parameters ? Heart Rate (HR), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), and Mean Arterial Pressure (MAP) ? from baseline following induction of anaesthesia and during pneumoperitoneum. Timepoint: From baseline (pre-induction) up to 15 minutes after creation of pneumoperitoneum.	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDR MAINA SINGH

Department of anesthesiology in jln medical College ajmer rajasthan

mainasingh111@gmail.com9414097045

Outcome results