Health Condition 1: Z682- Body mass index (BMI) 20-29, adult
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diabetic patients who have sarcopenic obesity with metabolic dysfunction-associated steatotic liver disease (MASLD). 2. can provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Compensated and decompensated liver cirrhosis. 2. Large Esophageal Varices. 3. HCC or any other malignancy 4. Poor cardiopulmonary reserve or other advanced systemic disease (other than diabetes mellitus) with expected survival less than 1 year. 5. Patient on the Use of semaglutide T2DM drugs known to induce weight loss (GLP-1 agonists like semaglutide, GLP1-A +GIP-A like Trizepatide) 6. Organ failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in sarcopenia and weight lossTimepoint: 1 Year | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion achieving 1. Improvement in sarcopenia 2. Target body weight 3. Maintaining Target body weight till end of study 4. Optimal glycemic control 5. Reduction in liver fat content Timepoint: 1 year | — |
Countries
India
Contacts
Mahatma Gandhi University of Medical Science & Technology