Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Nebulized dexmedetomidine 2 mcg/kg as premedication in attenuating the hemodynamic response to laryngoscopy and endotracheal intubation
: Comparison of 2 mcg/kg nebulized dexmedetomidin
Sponsors
Dr D G Rakshitha
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective surgeries under General Anaesthesia with endotracheal intubation 2. Patients belonging to American society of anaesthesiologist (ASA) Physical status (PS) grade 1 and 2 3. Mallampati class 1 and 2
Exclusion criteria
Exclusion criteria: 1. Patients with anticipated difficult airway 2. Patients with history of allergic reaction to Dexmedetomidine 3. Patient taking medications that alters the heart rate such as Beta-blockers and Clonidine 4. Pregnant patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the changes in Mean arterial pressure (MAP) as a component of haemodynamic stress response to laryngoscope and intubation with two doses, 1 mcg/kg versus 2 mcg/kg of nebulised DexmedetomidineTimepoint: Post-intubation at 1 minute, 2 minutes, 3minutes, 4 minutes, 5 minutes, 6 minutes, 8 minutes and 10 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the dose sparing effect of nebulised Dexmedetomidine on the amount of Propofol used during induction of General anaesthesia.Timepoint: Propofol induction dose(mg/kg) during induction of general anaesthesia | — |
Countries
India
Contacts
Public ContactDr. Aiyappa D S
Kodagu institute of medical scinces
Outcome results
None listed