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Improving Pain Relief in Bypass Surgery: A Study Using Two Common Medicines for injections to reduce pain

Efficacy of bupivacaine versus bupivacaine with dexamethasone as adjunct in pectointercostal fascial plane block for patients undergoing off pump coronary artery bypass A randomized control trial - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/094300
Enrollment
60
Registered
2025-09-08
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: injection of bupivacaine with dexamethasone: usg guided pectointercostal fascial plane block with bupivacaine plus dexamethasaone 20minutes before incision for surgery Control Intervent

Sponsors

Jawaharlal Nehru Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: age more than 18 years and less than 80 years off pump cabg surgery lv ejection fraction more than 45% midline sternotomy

Exclusion criteria

Exclusion criteria: allergy to local anesthetics preoperative pain medications bleeding disorders inr more than 1.5 emergency surgery

Design outcomes

Primary

MeasureTime frame
postoperative fentanyl requirement postoperative visual analogue scale scoreTimepoint: 24 hours after surgery—

Secondary

MeasureTime frame
arterial blood gas on pressure support ventilation time to tracheal extubation time to rescue analgesia time to ambulation total 24 hour opiod consumptionTimepoint: 24 hours—

Countries

India

Contacts

Public ContactRajesh Munigial

Jawaharlal Nehru Medical college

rajesh.munigial@gmail.com9341101240

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026