Comparison of Pregabalin and Gabapentin for reduction of preoperative anxiety

Comparison of Pregabalin and Gabapentin for preoperative anxiolysis: A randomised controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/094284

Enrollment

140

Registered

2025-09-04

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: PREGABALIN: Patients enrolled with group P will receive PREGABALIN 150mg one or two hours before surgery.Principal investigator and Patients will be blinded to the test group Control In

Eligibility

Inclusion criteria

Inclusion criteria: Adults ASA I/II/III Above 18 years Elective procedures All types of anaesthesia

Exclusion criteria

Exclusion criteria: Patient who does not give consent to the study Patients with anxiety score of 0 Allergy to pregabalin and gabapentin Abnormal liver/ renal function K/c/o cognitive and neurological disorder Pregnancy/breast feeding. H/o drug / alcohol abuse Patient on regular medication with pregabalin/gabapentin

Design outcomes

Primary

Measure	Time frame
To assess the reduction in preoperative anxiety between two drugs Timepoint: 6months-1 year	—

Secondary

Measure	Time frame
To assess the sedation score and side effects between two drugs Timepoint: 6months-1year	—

Countries

India

Contacts

Public ContactDrNandhinimurugesan

Dr.Rangarajan Memorial Hospital,

Lyndaprem@yahoo.com9976982196

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026