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A study in patients with lumbar spine problems comparing keyhole (minimally invasive) surgery and open surgery to see which causes less muscle damage and gives better recovery.

A Prospective Comparative Study of Minimally Invasive and Open Transforaminal Lumbar Interbody Fusion Assessing Biochemical Markers Muscle Damage and Clinical Outcomes - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/094200
Enrollment
50
Registered
2025-09-03
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M472- Other spondylosis with radiculopathy

Interventions

Intervention1: Blood tests - namely ESR, CRP, CK-MB, and LDH will be collected as part of routine preoperative workup: All these blood tests will be collected, and the results of these tests will be c

Sponsors

Ganesh Kumar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients who had undergone one level open/minimally invasive transforminal Lumbar fusion surgery

Exclusion criteria

Exclusion criteria: More than 2 level surgery, Patient who has undergone interbody fusion for infection, neoplasm, and deformity, Patients who underwent uninstrumented fusion, Age more than 60 years due to osteoporosis Patients operated for tandem canal stenosis, Ongoing psychiatric disease or under psychiatric care Infection during followup Muscular dystrophies, Inflammatory diseases Patients on antioxidants Patients who underwent any kind of physiotherapy or manipulation 1 day prior to the surgery and Neoplasm.

Design outcomes

Primary

MeasureTime frame
ESR, CRP, LDH, CK MB Timepoint: 12 hrs before and after surgery

Secondary

MeasureTime frame
Preoperative VAS and ODI Timepoint: 12 hrs before and after surgery

Countries

India

Contacts

Public ContactGanesh Kumar

Chief of Spine Services

vikas.spinesurgeon@gmail.com9597600553

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026