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Comparison of clinical and pathological findings in patients undergoing therapeutic corneal transplant

Clinicopathological correlation in therapeutic keratoplasty - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/094133
Enrollment
49
Registered
2025-09-02
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H160- Corneal ulcer Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Therapeutic keratoplasty: Preop cultures and staining reports collected followed by therapeutic keratoplasty and culture and histopathology of obtained corneal button .This includes ti

Sponsors

DrAtmakuru Sai Sivani
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Corneal ulcers of fungal,bacterial or acanthamoeba etiology, not responding to or showing progression despite a minimum of 2 weeks of medical therapy at our institute Corneal ulcer with impending perforation Perforated corneal ulcer more than 3mm Patients who give consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients with corneal ulcer caused by viruses Perforated corneal ulcer less than 3mm Patients age less than 15 or more than 70 with systemic conditions Infectious keratitis with endophthalmitis or panophthalmitis

Design outcomes

Primary

MeasureTime frame
Correlation of staining and culture reports preop with culture and histopathology reports of corneal button postopTimepoint: Preop and postop 1week

Secondary

MeasureTime frame
Assess predisposing factors for non healing infectious keratitisTimepoint: Preop 1week

Countries

India

Contacts

Public ContactVELURI HARITHA

sankara eye hospital,guntur

harithaveluri@sankaraeye.com6301133957

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026